IRDR Work Streams (WS) are one of the main forms of IRDR research cooperation. An IRDR WS is designed to address one or multiple research priorities of “A Framework for Global Science in Support of Risk-informed Sustainable Development and Planetary Health”. An IRDR WS is proposed by one or a group of research teams and its implementation is normally with the timeframe of 3-5 years. The proposals of IRDR WS are approved by IRDR Scientific Committee.